Dear Marcus,
Looks like the SAP system cannot access these external URLs. There could be many reasons, what goes wrong. The following WIKI page has several things to check:
Exception occurred in communication framework - Technology Troubleshooting Guide - SCN Wiki
Also, a level 3 ICM trace could be helpful: How to create a Level 3 ICM Trace - Technology Troubleshooting Guide - SCN Wiki
Best regards,
Attila